Insilico Medicine to present on recent advances in AI at BioData World in Cambridge

 Insilico Medicine, Inc to present on the recent advances in applying the deep learning techniques to biomarker development and drug discovery at the BioData World Congress in Cambridge, UK. Jane Schastnaya, a research scientist at Insilico Medicine, will give a presentation on October 27th in the "Genomics personalized medicine and biomarkers" track. 

"BioData World is one of the world's top conferences on bioinformatics bridging academia and industry, and I am very thankful to the organizers and our company for the opportunity to present our research at such a high-profile event. Insilico Medicine is clearly one of the leaders in the field with several "industry firsts" and events like BioData World allow us to find new challenges and sources of data that rapidly result in valuable research results. I will be presenting our work on applying deep learning techniques to estimating the chronological age of the patient using very simple blood tests as well as the comprehensive gene expression data. These biomarkers of aging are likely to be indicative of the overall health status and can be combined with the biomarkers of age-related diseases and used to improve clinical trials enrollment practices", said Jane Schastnaya, a research scientist at Insilico Medicine.

Sr. research scientist, pharmaceutical artificial intelligence (http://www.Pharma.AI) division will help with the Q&A and facilitate the discussion on applying the deep learning techniques to biomarker development and combining deep reinforcement learning and generative adversarial networks for drug discovery and establish collaborations with the top industry and academic thought leaders attending the conference.

The presentation titled "Actionable biomarkers of aging and disease trained on biochemistry and transcriptomics data" will cover the applications of deep learning techniques to large repositories of biomedical data and creating multi-modal biomarkers and predictors of therapeutic use of the drugs for high-throughput screening, deep-learned predictor of human age trained on human blood biochemistry and transcriptomics data. It will also cover the new method for deriving the importance of the features in deep networks soon to be published in a peer-reviewed journal. 

About Insilico Medicine

Insilico Medicine, Inc. is a bioinformatics company located at the Emerging Technology Centers at the Johns Hopkins University Eastern campus in Baltimore with R&D resources in Belgium, Russia and Poland hiring talent through hackathons and competitions. It utilizes advances in genomics, big data analysis and deep learning for in silico drug discovery and drug repurposing for aging and age-related diseases. The company pursues internal drug discovery programs in cancer, Parkinson's, Alzheimer's, sarcopenia and geroprotector discovery. Through its Pharma.AI division the company provides advanced machine learning services to biotechnology, pharmaceutical and skin care companies. Brief company video: https://www.youtube.com/watch?v=l62jlwgL3v8

About BioData World Congress

BioData World Congress is the world's leading event for individuals working with Big Data in precision medicine. The BioData World Congress UK partnered with the worlds of leading organizations: EMBL EBI, Genomics England, Sanger Institute and many others. The event will showcase innovation, demonstrate success and break through the obstacles and barriers to ensure that the innovations in genomics and big data enter the clinic with speed and efficiency. It will aim to make the dream of stratified medicine a reality. With hundreds of delegates from all over the world and thought leaders from the top academic, industry and governmental organizations, BioData World Congress is one of the main international events on data-driven personalized medicine. Website: http://www.healthnetworkcommunications.com/conference/biodatA/index.stm

Insilico Medicine and CBRM announce a licensing agreement

Insilico Medicine, Inc, and the Center for Biogerontology and Regenerative Medicine (CBRM) today entered into a licensing agreement, where Insilico obtained full rights to research results from experiments performed by and supported by the CBRM pertaining to in vitro validation of promising natural and pharmacological compounds.

In 2013 CBRM, a research organization headquartered in Moscow, Russia, sponsored a multi-center study, where multiple in silico predictions generated by scientists at Insilico Medicine were validated on in vitro on senescent cells and analyzed in multiple imaging and microarray experiments. A range of predictions with minimal or no side effects rescued the senescent phenotype and lead to transcriptomic signatures resembling "young" non-senescent cells. Insilico Medicine will receive the research results prior to publication in order to explore synergistic and cumulative effects of these compounds and perform further validation and compounding with the full rights to file for intellectual property and sub-license the findings.

The Center for Biogerontology and Regenerative Medicine is supporting multiple multi-disciplinary studies in aging and longevity, organizing industry forums and seminars for young scientists. It is dedicated to reducing Russia's dependence on natural resource-driven economy by fostering a generation of young leaders in systems biology of aging and longevity and age-related diseases. The study validating the efficacy of molecules with predicted geroprotective properties in vitro was one of the landmark research projects of CBRM.

"As a former employee of Insilico Medicine, I am happy to see that predictions we made using a novel computational approach can be validated in vitro and I hope to see this work propagate into clinical or preventative medicine practice within the coming decade. CBRM will continue performing cutting-edge experimental and clinical research to extend healthy longevity. We have one of the best teams of young scientists dedicated to preventing age-related diseases and debilitating aging-related conditions", said Andrew Garazha, president of CBRM.

About the Center for Biogerontology and Regenerative Medicine (CBRM)
 
The Center for Biogerontology and Regenerative Medicine was formed as a limited company in Russia to advance research in longevity research and regenerative medicine by a group of young scientists from the Pirogov Medical University, D. Rogachev Federal Research and Clinical Center for Pediatric Hematology, Oncology and Immunology, Moscow Institute of Physics and Technology (MIPT) and Lomonosov Moscow State University specializing in bioinformatics and medicine. CBRM is affiliated with the Skolkovo Foundation and is the resident of Biopharmcluster "Northern" at the Moscow Institute of Physics and Technology (MIPT) and has close collaborations and a research agreement with the laboratory of aging and longevity.
http://biogerontology.ru/en

About Insilico Medicine, Inc
 
Insilico Medicine, Inc. is a bioinformatics company located at the Emerging Technology Centers at the Johns Hopkins University Eastern campus in Baltimore. It utilizes advances in genomics, big data analysis and deep learning for in silico drug discovery and drug repurposing for aging and age-related diseases. The company pursues internal drug discovery programs in cancer, Parkinson's, Alzheimer's, sarcopenia and geroprotector discovery and provides services to pharmaceutical companies. Brief company video: https://www.youtube.com/watch?v=l62jlwgL3v8