2014-11-07

Insilico Medicine, Inc and Champions Oncology, Inc



Insilico Medicine, Inc announces research collaboration with Champions Oncology, Inc


Champions TumorGrafts are a personalized approach used to guide physician treatment decisions for cancer patients. A piece of the patient's living tumor is removed during surgery or biopsy and engrafted in immune-deficient mice. After the TumorGraft grows, still closely resembling the patient's tumor, Champions Oncology tests drug treatments in the TumorGraft and measures the response. TumorGraft has demonstrated high rates of predictability using multiple therapies, including single-agent and combination, chemotherapy regimens and targeted biological drugs.

Every TumorGraft is preserved as a living sample for future patient use. These banked TumorGrafts can be re-grown and tested in the event of cancer progression or recurrence. In oncology drug development, TumorGraft models are utilized extensively by pharmaceutical and biotechnology organizations to predict the clinical effectiveness of their compounds in targeted patient populations.

In the scope of this research collaboration Insilico Medicine will analyze a portion of Champions Oncology gene expression data sets from tumor grafts before and aftertreatment with chemotherapy drugs and compare the signaling pathway activation state (SPAS) changes with the SPAS changes in human patients.

Baltimore, MD, November 6, 2014 - Insilico Medicine, Inc, a Baltimore-based bioinformatics company focused on research in aging and age related diseases announced a research collaboration with the international leader in personalized medicine of cancer, Champions Oncology, Inc (OTC: CSBR).